One other important result was that patients treated with a single dose of prednisolone were statistically more likely to receive additional doses of the steroid compared to patients treated with 0.25 mg/kg/day. It is likely that this finding is related to the fact that the majority of patients treated with prednisolone were already being treated with glucocorticoids and were therefore in a hypocortisolemic state. In conclusion, this study demonstrated that oral glucocorticoid treatment has an effect on the levels of serum cortisol, but only in some of the patients. These patients were diagnosed with primary adrenal insufficiency and treated for hypogonadism, bulking 40 40 20. This finding confirms that glucocorticoid therapy is effective in reducing blood cortisol levels in patients with secondary adrenal insufficiency, prednisolone zentiva. However, it adds to the evidence that chronic glucocorticoid treatment may not be a safe option for the treatment of the secondary adrenal insufficiency.
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